Half Life: Approximately 70 minutes (after removing the patch)
Detection Time: 2-3 weeks
Effective Dose: 350-1000 mg/week (men); 50-100 mg/week (women)
Chemical Formula: C19 H28 O2
Molecular Weight: 288.424
Chemical Name: 4-androsten-3-one-17beta-ol
Androderm is a testosterone patch that uses a transdermal (through the skin) delivery system. Developed by TheraTech, a U.S. company based in Utah and approved as a prescription medication in 1995, Androderm is a synthetic androgen (male sex hormone) indicated for replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone. Although not highly practical as an independent performance enhancing steroid, due to its unique delivery system, Androderm does make a solid supplemental steroid cycle component (one added to an injectable or oral anabolic cycle).
Structurally speaking, Androderm’s chemical name is 4-androsten-3-one-17beta-ol, and its transdermal delivery system is a product of an alcoholic gel free testosterone housed within the patch by a drug reservoir. The transdermal release of testosterone occurs during the 24-hour patch application period, and at varying levels based on the specific patch dosage. The two primary dosages include 2.5 mg and 5 mg patches, which dispense 12.2 and 24.3 mg of testosterone respectively.
Athletes and bodybuilders don’t typically administer Androderm independently for anabolic purposes, but may use it in addition to other testosterone preparations as an ancillary testosterone additive (a supplemental amount to reach their total desired dosage). Such users benefit from numerous performance and physique-enhancing properties like:
EFFECTS OF ANDRODERM
A solid cutting compound, Androderm can be administered along with a healthy dieting and training regimen, to aid in the reduction of excess body fat while promoting lean muscle growth. Daily caloric restriction beyond 500 calories signals the body to slow down the metabolism, but the administration of Androderm counters this message by virtue of its affinity for the androgen receptors thereby increasing metabolic function during caloric deficit. An equally potent bulking agent, Androderm effectively stimulates muscle mass growth during off season training when athletes focus on getting bigger and stronger. Additionally, Androderm can be employed as a cruising/bridging compound that’s administered at low doses for the purpose of sustaining the cessation of natural testosterone production between anabolic cycles. Cruising affords the anabolic steroid user the ability to immediately return to the muscular growth phase upon initiation of the anabolic cycle.
A versatile anabolic compound, Androderm is safe for both male and female use, as well as for all levels of development from professional to recreational. Androderm is a dose dependent compound, and its impact on the individual user is contingent upon the dosages taken as well as the individual's dietary and training habits. However, the novice Androderm user has an average muscle gain of about 30 lbs when following the recommended administration protocol, a consistent weight training program, and a diet that's low in fat, high protein and low in sugar and processed foods. The benefit of dose dependency is that it allows lean athletes who may prize a very specific physique to customize their Androderm dosages, diet, and training for their particular goals.
Androderm, administration for performance enhancement purposes follows the same dosage guidelines as other forms of testosterone, specifically 350-1000 mg/week for men, and 50-100 mg/week for women.
Older versions of the testosterone patch were applied to the scrotum, but this not the case with Androderm nor should it be applied to bony areas on the body. Similar to injection spots, patches are optimally applied to areas where muscle is prevalent thereby permitting for full testosterone absorption and distribution. Individual patches should be removed, and replaced every 24 hours, and are best changed around the same time daily, e.g. upon waking, or at bedtime.
In conjunction with Androderm's benefits the user may experience a variety of negative side effects. These side effects are often well tolerated by adult males. However, whether side effects become merely bothersome or utterly unacceptable certain proven ancillary compounds can be administered to reduce their severity and in some cases completely resolved. Side effects can be categorized into very specific groups based largely on the wider Androderm quality that causes them. For example, some side effects are androgen related, others estrogen related, and still others result from the absence of natural testosterone during Androderm usage.
Testosterone is the most active of all androgens (more commonly known as male sex hormones). These androgens produce masculinizing effects that influence a wide variety of pre- and post-birth male development properties. They greatly impact the reproductive system and several bodily functions, as well as continue to exert masculinizing properties throughout the male’s life span. Produced as joint effort between the endocrine system and testes, testosterone is also the most prevalent androgen in the male body. When there is an androgen excess, beyond that naturally produced by the body as in Androderm use, the production of another hormone called dihydrotestosterone (DHT) also increases. DHT causes specific side effects such as: oily skin due to overly stimulated sebaceous glands which may result in varying degrees of acne on the face, back, and shoulders; accelerated (but not caused) male pattern baldness - a genetic hair loss condition; and enlargement of the prostate gland which is potentially harmful to the kidneys, bladder, and urinary tract.
The interaction between higher levels of testosterone (Androderm administration) and the aromatase enzyme causes the secretion of additional estrogen. Within men elevated estrogen levels promote side effects such as bloating - increased water and/or fluid retention. Although generally most prevalent within the midsection bloating impacts the whole body by reducing muscle separation, which in turn hinders overall muscular definition. If permitted to persist, bloating naturally escalates into what can be a very hazardous condition known as hypertension - an elevation of the blood pressure level which carries its own set of dangerous threats. Other common side effects caused by high estrogen levels are otherwise unexplained gains in overall body fat, and a higher risk of gynecomastia - a proliferation of the fatty/glandular component of the breast.
Aromatase inhibitors (AIs) are effective on cycle, estrogen-induced side effects resolving compounds. Undoubtedly the most popular AI choices are Arimidex, and Femara both of which inhibit aromatase at high enough levels (over 70% and over 80% respectively) to significantly reduce estrogenic side effects. Selective Estrogen Receptor Modulators (SERMs) represent another family of estrogen symptom nullifying compounds. Although not recommended on cycle because they can negatively affect anabolic cycle results, medications like Clomid (Clomiphene Citrate) and Nolvadex (Tamoxifen Citrate) both block aromatase absorption. These drugs permit the athlete to continue using estrogen (which plays a role in the muscle building process), without experiencing negative side effects. To reiterate, because SERMs have been clinically proven to negatively impact anabolic steroid cycle development, they make far better post-cycle therapy drugs than on cycle anti-estrogenic ones.
A common cardiovascular side effect of Androderm administration is negatively impacted cholesterol levels. By suppressing the body’s secretion of HDL cholesterol while increasing its secretion of LDL cholesterol, Androderm forces levels out of balance. Although not an especially dangerous side effect, it should be noted that any cholesterol testing will return abnormal levels. These changes are temporary, and the condition reverses not long after Androderm cycle discontinuation.
Androderm is such a strong anabolic steroid that it significantly suppresses endogenous testosterone secretion with only one application. Consequently, users can expect the complete cessation of endogenous testosterone production with continued use. An internal monitoring and reporting system, called the negative feedback loop, routinely updates the brain on internal bodily conditions. When a problem is detected homeostatic processes are initiated to return the system or level to normal. A classic physical example of this process is the way in which the body automatically perspires when it's too hot, and shivers when it's too cold. Since testosterone levels participate in the negative feedback loop, Androderm use effectively halts natural testosterone secretion. After Androderm discontinuation, and after the negative feedback loop has registered a substantial absence of testosterone, the brain sends the opposite message recommencing natural testosterone production. The period between Androderm discontinuation and the restoration of natural testosterone levels is known as the post-cycle, during which most steroid users employ post-cycle therapy (PCT) - the use of bridging compound for about 4-6 weeks, which is the typical time frame for natural testosterone restoration. SERMs, like Nolvadex (at 40 mg/day for the first week and 20 mg/day until the end) and Clomid (at 100 mg/day for the first week and 50 mg/day until the end) are generally administered as post-cycle therapy for approximately four weeks, or until normalcy is achieved. Additionally, Human Chorionic Gonadotropin (HCG) is often used at varying dosages to aid in elevating natural testosterone levels in those who experience complications restoring natural testosterone.
Androderm is not known to be a significantly liver toxic compound, and does not impose generally substantial stress on the liver functions.
Androderm is a prescription testosterone preparation that is legally available only through a physician. Primarily manufactured in the United States by Watson Labs, Androderm sometimes known as ATMOS, is also manufactured within several countries, and is found in both 2.5 mg and 5 mg dosages which administer (throughout a 24 hour period) 12.2 and 24.3 mg of testosterone respectively. Most likely due to its unique delivery system, and the lack of cost effectiveness, Androderm has not been reported as a counterfeited steroid.
As a synthetic testosterone, Androderm is (along with all other actual testosterones) classified by the United States Food and Drug Administration as a Class III controlled substance. As such, the Steroid Control Act of 1990, and the updated Steroid Control Act of 2004, makes it illegal to possess Androderm, or to buy Androderm online without a valid physician's prescription. Arrest and prosecution in a federal court of law awaits those found guilty of such an offense.
Although numerous online scammers exist, so do legitimate research laboratories, foreign pharmacies, and websites from which anabolic compounds can be purchased. Generally speaking, the best way to locate sources for legitimate anabolic agents is on established internet steroid forums, and at site Steroids.com which serves as an educational steroid-specific website whose sponsors market a variety of potent anabolics as well as a diversity of steroid-related ancillary compounds.
It is very rare that Androderm (the testosterone patch) is exclusively employed for effective performance enhancing benefit to the athlete, bodybuilder, and recreational fitness enthusiast. Generally speaking, the anabolic steroid cyclists will use Androderm as an ancillary additive to more practical injectable and oral steroid preparations. For example, Androderm is sometimes efficiently used as the low dose testosterone foundation required for preventing the erectile dysfunction complications which so often accompany Deca-Durabolin and Trenbolone cycles. Or, Androderm can be used to increase the amount of testosterone during a cycle. The most common complication with patch use is mathematical. The user must be sure to properly calculate, and administer Androderm dosing based on his or her daily anabolic steroid needs.